HPV Vaccine Safety: Causing Early Menopause?

hpv vaccine safety

Most parts of the globe has heard of HPV vaccine recommendation. However, some people still question HPV vaccine safety. There is a recent rumor spreading from an unknown source which (in case you haven’t heard) accused HPV vaccine for its early menopause effect. Official releases were made regarding this issue, and VaxCorp Indonesia already did all the readings for everyone’s clearer understanding.

The Facts

In case you forgot, in Indonesia there are 58 new findings of cervical cancer every single day. An Indonesian woman died every hour because of this preventable disease. HPV vaccine such as Gardasil® and Cervarix® are proven effective in giving 100% specific protection towards HPV type 16 and 18 (90% cause of cervical cancer). This protection may lasts for up to 14 years, in most people.

The Rumors About HPV Vaccine Safety

As an act of alarm, Indonesian Health Minister started a compulsory HPV vaccine program. The program targets towards elementary students aged 10-11 years old (as recommended by WHO). However, rumors are starting to spread that the HPV vaccine safety was questionable and instead would cause early menopause problem. Turns out, there are neither journals nor scientific release to confirm the causal relation between HPV vaccine administration and early menopause problem.

What The Experts Have Said

The American College of Paediatricians (The College) commits to the health and well-being of children. This naturally include measures taken for the prevention of diseases by vaccines. It has recently come to the attention of the College that one of the recommended vaccines are rumored to be associated with the very rare but serious condition of premature ovarian failure (POF). POF is also known as premature menopause. There have been two case report series (3 cases each) published since 2013. In these cases, adolescent girls developed laboratory documented POF within weeks to several years of receiving Gardasil®, a four-strain human papillomavirus vaccine (HPV4). Adverse events that occur after vaccines are frequently not a result of the vaccine. There has not been a noticeable rise in POF cases in the last 9 years since the wide use of HPV4 vaccine .

Numerous Gardasil® safety studies, including one released recently, have looked at demyelinating and autoimmune diseases and have not found any significant problems.

To Make Things Straight

Currently, there are 67 countries in the world implementing compulsory HPV vaccine programs. Distribution and administration have been more than 200 millions of HPV vaccine doses. WHO has certified these HPV vaccine’s safety based on continuous evaluations. These results, confirm that the HPV4 vaccine has a favorable safety profile. Hence, WHO has officially approved HPV vaccine including Gardasil® and Cervarix® for distribution since 2006.

Now that the facts are clear, please know that the rumors are simply rumors. Last but not least, it is nice that Indonesian health programs are going toward the better direction. If you have any further questions, please do not hesitate to contact VaxCorp Indonesia.

Infographics for HPV Vaccine Safety


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